IIn the first life decade acne and acne-like clinical patterns may occur quite frequently on the face of children, rarely on the integument.
POLECAMY
The anatomy and function of the skin in newborns and infants and also up to about the 8th year of life in children the sebaceous apparatus is not fully developed. The Anlage for the sebaceous gland is microscopically to be seen, however, the missing stimulus of insulin growth factor and of DHEA (dihydrotestosterone) acting in the preadolescent period has not started to enlarge the sebaceous gland and to produce significant amounts of sebum. The follicular openings host the microbiota with only very low numbers of Cutibacterium acnes playing no inflammatory role at this time. The newborn and infant ski...